Studies on N5-methyltetrahydrofolate-homocystein methyltransferase in normal and leukemia leukocytes.
نویسندگان
چکیده
منابع مشابه
Studies on Normal and Leukemic Leukocytes. v. Pyridine Nucleotide Transhydrogenases.
The function of these enzymes in vivo is not yet entirely clear, but the TD transhydrogenase may link TPNH to the mitochondrial electron transport system that oxidizes DPNH via molecular oxygen. The DD enzyme, alternatively, may function in the equilibration of free and mitochondrial-bound DPN (3). Hormonal influence on transhydrogenase reactions has been noted by Villee (5), who described the ...
متن کاملThe concentration of folic acid in leukocytes; observations on normal subjects and persons with leukemia.
that folic acid is essential forleukocyte maturation in the rat, and they thus established this vitamin as the first nutrient factor known to influence leukocyte production in a decisive manner. These observations have been abundantly confirmed and extended to include a variety of animal species (@, 8, 11). Since leukemia is characterized by excessive proliferation of leukocytes and their precu...
متن کاملCharacterization of N5-methyltetrahydrofolate uptake in cultured human retinal pigment epithelial cells.
PURPOSE To determine the identity of the transport process that is responsible for the uptake of N5-methyltetrahydrofolate, the predominant form of folate in blood, into cultured human retinal pigment epithelial cells. METHODS Human retinal pigment epithelial cells were cultured on an impermeable plastic support, and the characteristics of the uptake of radiolabeled N5-methyltetrahydrofolate ...
متن کاملBactericidal activity in fractionated granule contents from human polymorphonuclear leukocytes: studies with leukocytes from normal individuals.
Sephadex G-100 chromatographic fractions of granule extracts from normal human polymorphonuclear leukocytes, exhibiting differences from fractions previously obtained from leukemic polymorphonuclear leukocytes, possessed cationic proteins with distinct bactericidal activity against cell wall mutants of Salmonella typhimurium LT2.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1975
ISSN: 0021-9738
DOI: 10.1172/jci108205